MIQP is solved faster but unstable! Any suggestions for this?

Hello, I am solving a MIQP problem on MATLAB with YALMIP. At first, it is solved slowly. Therefore, I take the suggestion from https://support.gurobi.com/hc/en-us/community/posts/360075509811-How-to-solve-MIQP-faster-.

Specifically, I set

ops.gurobi.Method = 0;
ops.gurobi.AggFill = 10;
ops.gurobi.SimplexPricing = 2;

As a result, the settings boost the solving time. However, I found a new problem: the performance is unstable. Seems GUROBI reports me an unsatisfied solution in order to achieve short solving time as following.

Gurobi Optimizer version 9.1.0 build v9.1.0rc0 (mac64)
Thread count: 8 physical cores, 16 logical processors, using up to 16 threads
Optimize a model with 92180 rows, 35448 columns and 602966 nonzeros
Model fingerprint: 0x67be8d71
Model has 216 quadratic objective terms
Variable types: 26232 continuous, 9216 integer (9216 binary)
Coefficient statistics:
Matrix range [1e-03, 1e+04]
Objective range [2e-01, 5e+02]
QObjective range [8e+03, 8e+03]
Bounds range [1e+00, 1e+00]
RHS range [1e+00, 6e+02]
Presolve removed 62885 rows and 12696 columns
Presolve time: 0.84s
Presolved: 29295 rows, 22752 columns, 156268 nonzeros
Presolved model has 156 quadratic objective terms
Variable types: 15448 continuous, 7304 integer (7304 binary)
Extra simplex iterations after uncrush: 145
Warning: Markowitz tolerance tightened to 0.5
Warning: 1 variables dropped from basis

Root relaxation: objective 4.250163e+05, 35230 iterations, 1.96 seconds

Nodes | Current Node | Objective Bounds | Work
Expl Unexpl | Obj Depth IntInf | Incumbent BestBd Gap | It/Node Time

0 0 425016.319 0 272 - 425016.319 - - 3s

Explored 0 nodes (35230 simplex iterations) in 3.33 seconds
Thread count was 16 (of 16 available processors)

Solution count 0

Model is infeasible or unbounded
Best objective -, best bound 4.250163185197e+05, gap -
Time 6.346403 s.

But sometimes GUROBI can avoid this.

Gurobi Optimizer version 9.1.0 build v9.1.0rc0 (mac64)
Thread count: 8 physical cores, 16 logical processors, using up to 16 threads
Optimize a model with 92180 rows, 35448 columns and 602964 nonzeros
Model fingerprint: 0x38fdcf39
Model has 216 quadratic objective terms
Variable types: 26232 continuous, 9216 integer (9216 binary)
Coefficient statistics:
Matrix range [1e-03, 1e+04]
Objective range [2e-01, 5e+02]
QObjective range [8e+03, 8e+03]
Bounds range [1e+00, 1e+00]
RHS range [1e+00, 6e+02]
Presolve removed 62984 rows and 12634 columns
Presolve time: 1.27s
Presolved: 29196 rows, 22814 columns, 154283 nonzeros
Presolved model has 156 quadratic objective terms
Variable types: 15512 continuous, 7302 integer (7302 binary)
Extra simplex iterations after uncrush: 144
Warning: Markowitz tolerance tightened to 0.5
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 2 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 2 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 2 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 2 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis
Warning: 1 variables dropped from basis

Root relaxation: objective 4.825983e+05, 37709 iterations, 3.88 seconds

Nodes | Current Node | Objective Bounds | Work
Expl Unexpl | Obj Depth IntInf | Incumbent BestBd Gap | It/Node Time

0 0 482598.261 0 292 - 482598.261 - - 5s
H 0 0 2253811.6440 482598.261 78.6% - 6s
H 0 0 1305030.4395 482598.261 63.0% - 6s
H 0 0 1245003.7128 482598.261 61.2% - 7s
0 0 483540.119 0 259 1245003.71 483540.119 61.2% - 8s
H 0 0 489896.61436 483540.119 1.30% - 8s
0 0 483549.282 0 250 489896.614 483549.282 1.30% - 8s
0 0 483552.537 0 248 489896.614 483552.537 1.29% - 8s
0 0 483627.076 0 300 489896.614 483627.076 1.28% - 9s
0 0 483629.592 0 276 489896.614 483629.592 1.28% - 9s
0 0 483629.592 0 276 489896.614 483629.592 1.28% - 9s
0 0 483667.905 0 248 489896.614 483667.905 1.27% - 10s
H 0 0 487639.99441 483667.905 0.81% - 10s

Cutting planes:
Gomory: 6
Implied bound: 165
MIR: 93
Flow cover: 116
Relax-and-lift: 97

Explored 1 nodes (40663 simplex iterations) in 10.69 seconds
Thread count was 16 (of 16 available processors)

Solution count 5: 487640 489897 1.245e+06 ... 2.25381e+06

Optimal solution found (tolerance 1.00e-02)
Best objective 4.876399944116e+05, best bound 4.836679052713e+05, gap 0.8146%
Time 14.390970 秒.

The ratio of first bad case to second good case is about 4/6. Could you please share any suggestions with me to avoid/balance this?

Thanks,

Xianbang